Dissolution is beautiful
SOTAX is a global leader in providing high-quality dissolution testing systems, automated sample preparation workstations for content uniformity, assay and blend uniformity testing, as well as physical tablet testing instruments for the pharmaceutical, dietary supplement, medical device and biopharmaceutical industries.
Sotax offers complete system integration with method development, qualification and maintenance contracts. The SOTAX Group has offices in Switzerland, the United States, Canada, France, Germany, Italy, the Czech Republic, the United Kingdom, Thailad, India, and China with a vast global distribution network for local support and service solutions.
Dissolution Testing
When a substance forms a solution, this process is called Dissolution. When performing the test with a dissolution tester, the release rate and total drug amount over time is measured. The dissolution rate/amount of an Active Pharmaceutical Ingredient (API) is important for correlating product safety and efficacy. Through a consolidated effort, the instruments used to generate a dissolution rate have been standardised through various compendial initiatives.
Dissolution testing uses a defined setup with specific conditions to evaluate the performance of the product. Compendia describes seven standardised dissolution apparatus, the most commonly dissolution equipment used being basket (USP 1), paddle (USP 2) and flow-through cell (USP 4).
Physical Testing
Solutions to test the physical properties of tablets, capsules and other solid dosage form. With a proven track record of more than 25’000 testers in the market, SOTAX tablet hardness testers and disintegration testers are known for their reliability, precision and ease of operation. Robust devices for friability testing and for determining powder & granulate characteristics complete the range of solid dosage testers. All instruments can be operated stand-alone and are ready for seamless integration with powerful data management software for consolidated batch reporting in full compliance with 21 CFR part 11 requirements.
Automated Sample Preparation
Volumetric preparation of solid / liquid oral dosage forms, API, creams and pastes requires accurate execution of multiple laborious steps. Automated sample preparation enhances laboratory productivity by minimising resource allocation for repetitive tasks such as sample weighing, extraction, filtration, dilution, and transfer to analysis devices. This enables the re-purposing of lab staff to mission critical tasks such as data analysis, reporting, and notebook documentation. Automated procedures can also reduce solvent usage and hazardous waste generation while improving analyst safety by minimising exposure to hazardous reagents and samples.
AAT 